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	<title>Next Pharmaceuticals</title>
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	<description>News, Research and Information Next Pharmaceuticals</description>
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		<title>Studies Shows Gender Plays Role in Relationship between Health &amp; Sleep</title>
		<link>http://nextpharmaceuticals.com/nextword/studies-shows-gender-plays-role-in-relationship-between-health-sleep/</link>
		<comments>http://nextpharmaceuticals.com/nextword/studies-shows-gender-plays-role-in-relationship-between-health-sleep/#comments</comments>
		<pubDate>Thu, 09 May 2013 00:04:22 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/studies-shows-gender-plays-role-in-relationship-between-health-sleep/</guid>
		<description><![CDATA[A study out of Duke University Medical Center provided the first empirical evidence that gender has an effect on sleep and health. It observed 210 healthy, middle-aged men and women who had no history of sleep disorders. Sleep quality was measured by the amount of sleep, extent of awakening during the night, and time until [...]]]></description>
			<content:encoded><![CDATA[<p>A study out of Duke University Medical Center provided the first empirical evidence that gender has an effect on sleep and health. It observed 210 healthy, middle-aged men and women who had no history of sleep disorders. Sleep quality was measured by the amount of sleep, extent of awakening during the night, and time until falling asleep.</p>
<p>&#8220;We found that for women, poor sleep is strongly associated with high levels of psychological distress, and greater feelings of hostility, depression and anger,&#8221; said researcher Suarez. Men experiencing the same degree of poor sleep did not have this reaction.</p>
<p>The sleep indicator that suggested to be most impactful was the amount of time it took to fall asleep. Those who took 30 minutes or longer to fall asleep had the worst risk profile for diseases such as heart disease and diabetes.</p>
<p>As new as this information may seem, the study was conducted in 2008. Since then, numerous studies have delved deeper into the negative effects poor sleep has on health. Poor sleep affects not only heart health and insulin levels, but it also impacts memory, stress levels, weight gain, and other body functions. Calling to attention that it is women who are most affected by poor sleep, it is even more important for them to make a conscious effort to improve their sleep situations.</p>
<p>For those who have trouble falling asleep at night, an all-natural dietary supplement such as Seditol® may help. Seditol has the capability to help people fall asleep faster and stay asleep longer without side effects or “hangover” the next morning. </p>
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		<title>Severity of Erectile Dysfunction and Risk of Cardiovascular Disease Shown to be Directly Correlated</title>
		<link>http://nextpharmaceuticals.com/nextword/severity-of-erectile-dysfunction-and-risk-of-cardiovascular-disease-shown-to-be-directly-correlated/</link>
		<comments>http://nextpharmaceuticals.com/nextword/severity-of-erectile-dysfunction-and-risk-of-cardiovascular-disease-shown-to-be-directly-correlated/#comments</comments>
		<pubDate>Sun, 03 Feb 2013 20:59:09 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>
		<category><![CDATA[erectile dysfunction]]></category>
		<category><![CDATA[Flavoxine]]></category>
		<category><![CDATA[heart health]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=326</guid>
		<description><![CDATA[A study published January 29th in the journal PLOS Medicine built on past research studying the relationship between erectile dysfunction (ED) and increased risk of heart disease. While studies have recognized ED as a risk marker for cardiovascular disease (CVD) among previously undiagnosed men, this study examined whether worsening ED is related to an increased [...]]]></description>
			<content:encoded><![CDATA[<p>A study published January 29th in the journal PLOS Medicine built on past research studying the relationship between erectile dysfunction (ED) and increased risk of heart disease. While studies have recognized ED as a risk marker for cardiovascular disease (CVD) among previously undiagnosed men, this study examined whether worsening ED is related to an increased risk of a cardiovascular event.</p>
<p>A group of 123,775 men, aged 45 years and older were selected at random. The results showed that the risk of cardiovascular disease increased consistently with the severity of ED. Furthermore, men with severe erectile dysfunction and no previous diagnoses of CVD had an increased risk of ischemic heart disease, heart failure, peripheral vascular disease, and a 93% increased risk of all-cause mortality.</p>
<p>Although arterial, hormonal, psychological, and other causes for ED exist, it is now widely believed that ED is most often due to cardiovascular health. Scientists emphasize that ED is a risk marker for CVD, neither a symptom nor cause of it. Hypotheses suggest that the reason for ED being a marker of cardiovascular health is that the atherosclerotic disease may first manifest in smaller blood vessels, such as those in the penis.</p>
<p>Flavoxine is an all-natural supplement that supports cardiovascular health and weight management ideal for those looking for a natural solution for heart health.</p>
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		<title>New Study Shows Sleep Does More for Health than Rest Your Brain</title>
		<link>http://nextpharmaceuticals.com/nextword/new-study-shows-sleep-does-more-for-health-than-rest-your-brain/</link>
		<comments>http://nextpharmaceuticals.com/nextword/new-study-shows-sleep-does-more-for-health-than-rest-your-brain/#comments</comments>
		<pubDate>Fri, 21 Dec 2012 16:23:28 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=321</guid>
		<description><![CDATA[A study published in the Annals of Internal Medicine suggest that sleep deprivation may cause fat cells to change in a way that makes them react like those of an obese or diabetic person. The study focused on sleep deprivation and its relationship to subcutaneous fat, specifically, a critical tissue in energy metabolism and balance. [...]]]></description>
			<content:encoded><![CDATA[<p>A study published in the Annals of Internal Medicine suggest that sleep deprivation may cause fat cells to change in a way that makes them react like those of an obese or diabetic person. The study focused on sleep deprivation and its relationship to subcutaneous fat, specifically, a critical tissue in energy metabolism and balance. It also demonstrated that ongoing sleep deprivation in combination with disruption of circadian cycles decreases resting metabolic rate. This clinical study is significant because it is the first to demonstrate a causal relationship between sleep deprivation and an alteration of the molecular metabolic pathway.</p>
<p>The short-term studies suggested that sleep deprivation impairs glucose tolerance and overall energy, while increasing insulin resistance and appetite. The effect of sleep deprivation on insulin sensitivity was significant, showing a 30% reduction in peripheral insulin sensitivity. If continued over a long period, it is believed that it may be linked to the development of diabetes and obesity.</p>
<p>The results of the study lead researchers to believe that further studies on sleep deprivation may show that it also plays a role in other diseases, including cancer.</p>
<p>For those who struggle with restful sleep, Seditol® is an all-natural alternative that has the capability to help people fall asleep faster and stay asleep longer without feeling groggy or “hungover” the next morning.</p>
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		<title>Obesity in Majority of American Population Projected by 2030</title>
		<link>http://nextpharmaceuticals.com/nextword/obesity-in-majority-of-american-population-projected-by-2030/</link>
		<comments>http://nextpharmaceuticals.com/nextword/obesity-in-majority-of-american-population-projected-by-2030/#comments</comments>
		<pubDate>Wed, 31 Oct 2012 19:56:44 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=317</guid>
		<description><![CDATA[A recent report by The Trust for America’s Health and the Robert Wood Johnson Foundation reports that given current trends, by 2030, more than half of Americans could be obese. For the first time, the annual report also looked at forecasted obesity-related disease rates and health care costs. Currently, about 1/3 of all deaths from [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.healthyamericans.org/report/100/" target="_blank">A recent report</a> by The Trust for America’s Health and the Robert Wood Johnson Foundation reports that given current trends, by 2030, more than half of Americans could be obese. For the first time, the annual report also looked at forecasted obesity-related disease rates and health care costs. Currently, about 1/3 of all deaths from cancer each year are related to obesity, poor nutrition or physical activity. By 2030, projections are worse.</p>
<p>Entitled F as in Fat: How Obesity Threatens America’s Future 2012, highlights from the projected statistics given current trends include the following:<br />
•	The number of new cases of type 2 diabetes, coronary heart disease and stroke, hypertension and arthritis could increase 10 times between 2010 and 2020-and double again by 2030.<br />
•	Medical costs of treating preventable obesity-related diseases will increase $18 billion per year in the US with the overall cost of adult obesity estimated to be as high as $210 billion per year.<br />
•	The percentage of obese individuals will almost double in many states across the country, hitting as high as 66% in Mississippi and Oklahoma.</p>
<p>According to the study, even reductions as little as 5% in Body Mass Index (BMI) would spare, in California alone, 656,970 people from coronary heart disease and stroke, 796,430 people from Type 2 diabetes, 387,850 from arthritis and 52,796 from obesity-related cancer.</p>
<p>Exercise, health diet, good sleep and low stress levels are all contributors to a healthy lifestyle. Relora® for stress and weight loss management and Seditol® for restful sleep may help those looking to improve their overall health and beat the projections of obesity in the coming years.</p>
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		<title>New Study Finds Effect of Parents’ Stress on Children’s Health</title>
		<link>http://nextpharmaceuticals.com/nextword/new-study-finds-effect-of-parents%e2%80%99-stress-on-children%e2%80%99s-health/</link>
		<comments>http://nextpharmaceuticals.com/nextword/new-study-finds-effect-of-parents%e2%80%99-stress-on-children%e2%80%99s-health/#comments</comments>
		<pubDate>Wed, 24 Oct 2012 16:33:09 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=314</guid>
		<description><![CDATA[A study, published in the October issue of Pediatrics, examined the link between stressed parents and obesity and other behaviors in their children. Behaviors included physical exercise and consumption of fruits and vegetables.
The study found that parent stress is directly related to child obesity. The number one behavior correlated to parental stress was fast-food consumption, [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://pediatrics.aappublications.org/content/early/2012/10/15/peds.2012-0895.abstract">A study, published in the October issue of Pediatrics</a>, examined the link between stressed parents and obesity and other behaviors in their children. Behaviors included physical exercise and consumption of fruits and vegetables.</p>
<p>The study found that parent stress is directly related to child obesity. The number one behavior correlated to parental stress was fast-food consumption, an indicator of obesity risk. According to one psychologist at Children’s National Medical Center in Washington, D.C., “We do see this in clinical practice. Parents are often stressed and have a hard time providing healthy options”. This can be due to financial and/or time pressures.</p>
<p>Within the study findings, a few demographic groups suggested to be more susceptible to the parent stress-child obesity link: children from single-parent households, children from families struggling financially, and black/Hispanic children.</p>
<p>Relora® may be an option for parents looking to decrease stress levels naturally when time is not available to exercise and take time out for themselves. With the findings linking parental stress and childhood obesity, stress management becomes a priority not only for parents’ own health, but for their children’s health as well.</p>
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		<title>Recent Studies Suggests Chronic Stress &amp; Type A Personality Traits Increase Risk of Stroke</title>
		<link>http://nextpharmaceuticals.com/nextword/recent-studies-suggests-chronic-stress-type-a-personality-traits-increase-risk-of-stroke/</link>
		<comments>http://nextpharmaceuticals.com/nextword/recent-studies-suggests-chronic-stress-type-a-personality-traits-increase-risk-of-stroke/#comments</comments>
		<pubDate>Tue, 11 Sep 2012 12:36:51 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=310</guid>
		<description><![CDATA[A recent study published in the Journal of Neurology, Neurosurgery and Psychiatry studied the relationship between psycho-physical stress and stroke, while also examining how this is affected by gender.
The study, conducted at the Universitario San Carlos in Madrid, Spain, examined 450 individuals with an average age of 54. Though younger than the average stroke victim, [...]]]></description>
			<content:encoded><![CDATA[<p>A recent study published in the <a title="http://jnnp.bmj.com/content/early/2012/07/30/jnnp-2012-302420.abstract" href="http://" target="_blank">Journal of Neurology, Neurosurgery and Psychiatry</a> studied the relationship between psycho-physical stress and stroke, while also examining how this is affected by gender.</p>
<p>The study, conducted at the Universitario San Carlos in Madrid, Spain, examined 450 individuals with an average age of 54. Though younger than the average stroke victim, the target age was selected because high blood pressure and other health issues related to stroke often have not yet taken affect.</p>
<p>The study unveiled a number of findings related to stress and stroke. First, the study concluded that that chronic stress and type A behavior are associated with high risk of stroke and may increase the risk of stroke up to 200%. This is not affected by gender. Secondly, other factors that may increase the risk of stroke may include a history of smoking or drinking two or more energy drinks a day, the latter of which came as a surprise to researchers.</p>
<p>According to researcher Ana Maria Garcia, “Our findings indicate that people can lower their stroke risk by attempting to reduce the stress in their lives”. The research suggests yet another critical reason to control stress levels. <a href="http://nextpharmaceuticals.com/stage/?q=node/11" target="_blank">Relora®</a>, an all-natural dietary supplement to alleviate stress, is one of the top products in its category and the most powerful anti-stress supplement on the market.</p>
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		<title>Washington State School of Medicine Discovers Connection Between Gene Presence and Sensitivity to Taste of Fat</title>
		<link>http://nextpharmaceuticals.com/nextword/washington-state-school-of-medicine-discovers-connection-between-gene-presence-and-sensitivity-to-taste-of-fat/</link>
		<comments>http://nextpharmaceuticals.com/nextword/washington-state-school-of-medicine-discovers-connection-between-gene-presence-and-sensitivity-to-taste-of-fat/#comments</comments>
		<pubDate>Sat, 14 Jul 2012 21:40:35 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=306</guid>
		<description><![CDATA[Scientists at Washington State University are claiming to have discovered a sixth sense: the taste for fat. The study findings, detailed in a recent report by the Washington University School of Medicine and published in The Journal of Lipid Research, studied over 20 adults and found that those with the “CD36” gene were more sensitive [...]]]></description>
			<content:encoded><![CDATA[<p>Scientists at <a href="http://news.wustl.edu/news/Pages/23206.aspx" target="_blank">Washington State University</a> are claiming to have discovered a sixth sense: the taste for fat. The study findings, detailed in a recent report by the Washington University School of Medicine and published in The Journal of Lipid Research, studied over 20 adults and found that those with the “CD36” gene were more sensitive to the taste of fat and less prone to obesity.</p>
<p>The researchers hypothesized that people with highly fatty diets may produce less CD36 protein, making them less sensitive to fatty foods and, consequently, more likely to intake fat.</p>
<p>The research-the first of its kind to identify a human receptor that can taste fat-appears to support previous findings that obesity is linked to genes as well as a person&#8217;s diet.  The study also found that nearly 20 percent of Americans are likely to produce less CD36 and are therefore less sensitive to the taste of fatty foods.</p>
<p>People who suffer from obesity are at an elevated risk for cardiovascular disease, stroke, diabetes, and arthritis. Relora, an all-natural blend of Magnolia officinalis bark extract and Phellodendron amurense bark extract, is the leading all-natural dietary supplement to alleviate stress, stress-related eating and promote weight management.</p>
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		<title>Sleep Disorders Found to be Widespread among Police</title>
		<link>http://nextpharmaceuticals.com/nextword/sleep-disorders-found-to-be-widespread-among-police/</link>
		<comments>http://nextpharmaceuticals.com/nextword/sleep-disorders-found-to-be-widespread-among-police/#comments</comments>
		<pubDate>Wed, 20 Jun 2012 01:08:42 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=303</guid>
		<description><![CDATA[Researchers from Brigham and Women&#8217;s Hospital in Boston have produced findings indicating that 40 percent of police officers nationwide suffer from sleep disorders.  The study, published in the December edition of the Journal of the American Medical Association, was based on survey data taken of 5,000 police officers throughout the country over a period [...]]]></description>
			<content:encoded><![CDATA[<p>Researchers from Brigham and Women&#8217;s Hospital in Boston have produced findings indicating that 40 percent of police officers nationwide suffer from sleep disorders.  The study, published in the December edition of the <em>Journal of the American Medical Association</em>, was based on survey data taken of 5,000 police officers throughout the country over a period of two years.</p>
<p>The study indicated that those surveyed were more likely to report making administrative errors, fall asleep while driving, express anger toward citizens or suspects, and commit safety violations as a result of their sleeping disorders. Police departments nationwide have responded by lowering shift hours and initiated other regulations intended to address reported symptoms.</p>
<p>According to the findings, an estimated 50 to 70 million Americans suffer from sleep disorders, including sleep apnea or insomnia, and most who suffer are undiagnosed. Along with a healthy diet, reassessment of shift conditions, and professional medical advice, persons suffering from a sleep disorders may consider all-natural dietary supplements, such as Seditol®, which has been shown through multiple clinical trials to promote relaxation and sleep.</p>
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		<title>Scripps Research Team Discovers New Chemical Compound Said to Block Enzyme Linked to Inflammation.</title>
		<link>http://nextpharmaceuticals.com/nextword/scripps-research-team-discovers-new-chemical-compound-said-to-block-enzyme-linked-to-inflammation/</link>
		<comments>http://nextpharmaceuticals.com/nextword/scripps-research-team-discovers-new-chemical-compound-said-to-block-enzyme-linked-to-inflammation/#comments</comments>
		<pubDate>Thu, 14 Jun 2012 20:35:02 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=301</guid>
		<description><![CDATA[In a new study published by the journal, ACS Chemical Biology, scientists at the Scripps Research Institute have developed a new chemical compound which has been shown to block the presence of PRMT1, an enzyme linked to inflammation in individuals suffering from arthritis.
The study findings will be useful to scientists who are developing new drug [...]]]></description>
			<content:encoded><![CDATA[<p>In a new study published by the journal, ACS Chemical Biology, scientists at the Scripps Research Institute have developed a new chemical compound which has been shown to block the presence of PRMT1, an enzyme linked to inflammation in individuals suffering from arthritis.</p>
<p>The study findings will be useful to scientists who are developing new drug treatments for PRMT1-related ailments and for targeting specific enzymes in the human body. It also moves scientists one step closer to identifying the enzyme responsible for nearly all arginine methylation present in mammalian cells.</p>
<p>To date scientists have been unable to distinguish between compounds inhibiting PRMT1 and those blocking the larger PRMT family of enzymes. This was largely due to the fact that scientists could not distinguish between PRMT1 and the 10 other PRMT enzymes due to their structural and biochemical similarities.</p>
<p>As research continues to explore the link between the development of these enzymes and inflammation, individuals suffering from symptoms relating to inflammation seek out remedies to alleviate their pain.  There are currently countless prescription anti-inflammatories available on the market as well as a few supplements.</p>
<p>Nexrutine, an all-natural dietary supplement produced from the proprietary blend of actives extracted from the bark of Phellodendron amurense, acts to inhibit enzymes related to inflammation and is shown to safely and effectively help avoid or relieve the general aches and pains associated with physical activity or over-exertion.</p>
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		<title>Harmonease® May Reduce Stress-Related Behaviors in Dogs</title>
		<link>http://nextpharmaceuticals.com/nextword/harmonease%c2%ae-may-reduce-stress-related-behaviors-in-dogs/</link>
		<comments>http://nextpharmaceuticals.com/nextword/harmonease%c2%ae-may-reduce-stress-related-behaviors-in-dogs/#comments</comments>
		<pubDate>Mon, 05 Mar 2012 16:57:14 +0000</pubDate>
		<dc:creator>ashleyh</dc:creator>
				<category><![CDATA[uncategorized]]></category>

		<guid isPermaLink="false">http://nextpharmaceuticals.com/nextword/?p=299</guid>
		<description><![CDATA[The Journal of Veterinary Behavior recently published a study to test the effects Harmonease has on fear and anxiety in dogs. Harmonease is a product developed for the veterinary channel that contains a proprietary blend of extracts from the bark of Magnolia officinalis, and the bark of Phellodendron amurense
Twenty beagle dogs in good health and [...]]]></description>
			<content:encoded><![CDATA[<p>The Journal of Veterinary Behavior recently published a study to test the effects Harmonease has on fear and anxiety in dogs. Harmonease is a product developed for the veterinary channel that contains a proprietary blend of extracts from the bark of Magnolia officinalis, and the bark of Phellodendron amurense</p>
<p>Twenty beagle dogs in good health and between 4 and 8 years old were selected for the study. Thunderstorm sounds were reproduced using a sound desensitization compact disc shown to be effective for behavior modification programs for noise-related anxieties. The beagles were video recorded for 9 minutes: a 3 minute anticipatory phase, a 3 min. thunderstorm phase and a 3 min. recovery phase.</p>
<p>One group received the placebo during the first treatment period and the other received Harmonease. On day 13, dogs were again subjected to the thunderstorm testing and the treatment groups were crossed over so that dogs receiving Harmonease during the first treatment period received the placebo during the second treatment period and vice versa.</p>
<p>The model measured stress-related clinical signs during the test such as distance travelled by the dog, inactivity duration and inactivity frequency &#8211; all related to freezing responses and the most robust measures of anxiety in this test.</p>
<p>The test facility was operated in accordance with guidelines set forth by the Canadian Council on Animal Care. Animal housing and care met or exceeded all applicable provincial and Federal regulations, and the study protocol was approved by the test facility’s Animal Care Committee.</p>
<p>Sixty percent (60%) of dogs improved from baseline when treated with Harmonease, whereas only 25% improved on placebo. Furthermore, Harmonease has a comparatively low risk of producing side effects such as central depression, muscle relaxation, or amnesia as compared to benzodiazepines, commonly used to address anxiety in dogs.</p>
<p>The study concluded that Harmonease reduced fear-related inactivity or freezing in dogs in this thunderstorm simulation model. This supports past studies demonstrating that the combination of botanical extracts in Harmonease is effective in dogs for the management of stress-related behaviors.</p>
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