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Tynept 12.5mg (Tianeptine)

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Description

Tynept (Tianeptine) is a prescription medicine manufactured by Intas Pharmaceuticals. It is an atypical antidepressant, with a significantly different chemical to most antidepressants that are used today. It is most commonly used to treat symptoms of depressive disorders, and as it works in an alternative way to SSRIs, it may be prescribed for patients who have failed to respond to treatment using typical antidepressants.

How Tianeptine Works

Tynept tablets contain 12.5mg of the active ingredient Tianeptine. Unlike SSRIs which inhibit reuptake of serotonin (the body’s ‘happy hormone’) to increase levels within the central nervous system, Tianeptine interacts with opioid receptors to build the body’s own natural ability to prevent reuptake of monoamines such as serotonin and dopamine. Tianeptine does not actively or directly alter levels of monoamines, but helps the body to maintain stable levels. It’s known as a serotonin reuptake enhancer.

Tianeptine Uses

Tynept (Tianeptine) is often prescribed to treat:

  • Major depression
  • Bipolar-related depression
  • Persistent depressive disorders such as dysthymia
  • Treatment-resistant depression

Tianeptine Dosage

The usual dose for Tynept 12.5mg is one tablet taken three times a day; morning, midday, and evening, However, it is important to take the medicine as advised by the prescribing doctor. A lower dose of two tablets per day may be recommended for older patients, and for those with kidney problems. Never exceed the prescribed dose.

It is best to take Tynept 12.5mg tablets with food, or just before a meal. It is recommended that patients do not consume alcohol while taking Tynept 12.5mg.

Tianeptine Side Effects

Tynept is generally considered to be safe when taken as prescribed. However, as with many medications, some patients may experience mild side effects, including:

  • Nausea and vomiting
  • Constipation and gastrointestinal discomfort
  • Pain in the stomach or abdomen
  • Headache
  • Dizziness
  • Disturbed sleep
  • Vivid dreams or nightmares

Due to the risk of dizziness, it is important to refrain from driving or operating heavy machinery initially, until you know how your body responds to Tynept 12.5mg.

It is important for patients to read the patient information leaflet in the packaging for a full list of possible side effects from taking Tynept 12.5mg. Always consult with the prescribing doctor if side effects persist. If experiencing difficulty breathing, call 999.

References

  1. https://pubmed.ncbi.nlm.nih.gov/11463130/
  2. https://www.sciencedirect.com/topics/neuroscience/tianeptine
  3. https://www.healthline.com/health-news/controversy-over-antidepressant-tianeptine#The-abuse-problem
  4. https://www.elsevier.es/en-revista-revista-psiquiatria-salud-mental-486-articulo-tianeptine-an-atypical-pharmacological-approach-S217350501930038X
  5. http://mri.cts-mrp.eu/download/PT_H_0453_001_FinalPL.pdf

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